Between 1600 and 1750, the Jesuit founded more than sixty reductions in the
south of Brazil, north of Argentine and in Paraguay.
These missions were constantly attacked by
bandeirantes coming from São Paulo.
The attacks only decreased after the battle of M´bororé, where 3.000 Guaraní Indians supported by the Jesuit priests
Pedro Romero and Pedro de Mola defeated the
bandeira of Jerônimo de Barros, which was formed of 300
paulistas
and 600 Tupi Indians.
Due to territorial disputes (
seven villages), the Jesuit were expelled of Brasil in 1759 by the Marquês de Pombal.
It was also the end of the
hereditary captaincies.